Isoflurane and Sevoflurane Induce Severe Hepatic Insulin Resistance in a Canine Model.
Stella P KimJosiane L BroussardCathryn M KolkaPublished in: PloS one (2016)
Inhaled anesthesia induces severe hepatic insulin resistance in a canine model. Countermeasures that preserve hepatic insulin sensitivity may represent a therapeutic target that could improve surgical outcomes in both diabetic and healthy patients.