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Isoflurane and Sevoflurane Induce Severe Hepatic Insulin Resistance in a Canine Model.

Stella P KimJosiane L BroussardCathryn M Kolka
Published in: PloS one (2016)
Inhaled anesthesia induces severe hepatic insulin resistance in a canine model. Countermeasures that preserve hepatic insulin sensitivity may represent a therapeutic target that could improve surgical outcomes in both diabetic and healthy patients.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • early onset
  • chronic kidney disease
  • peritoneal dialysis
  • cystic fibrosis
  • patient reported outcomes