Increased pore size of scaffolds improves coating efficiency with sulfated hyaluronan and mineralization capacity of osteoblasts.
Jan KrieghoffAnn-Kristin PickeJuliane Salbach-HirschSandra RotherChristiane HeinemannRicardo BernhardtChristian KascholkeStephanie MöllerMartina RaunerMatthias SchnabelrauchVera HintzeDieter ScharnweberMichaela Schulz-SiegmundMichael C HackerLorenz C HofbauerChristine HofbauerPublished in: Biomaterials research (2019)
In summary, we showed that the improvement of scaffold pore sizes enhanced the coating efficiency with collagen and sHA3, which had a significant positive effect on bone formation markers, underlining the promise of using this material approach for in vivo studies.