Integrative genomics analysis of various omics data and networks identify risk genes and variants vulnerable to childhood-onset asthma.

Xiuqing MaPeilan WangGuobing XuFang YuYunlong Ma

Published in: BMC medical genomics (2020)

We provide strong evidence to highlight 31 candidate genes for childhood-onset asthma risk, and offer a new insight into the genetic pathogenesis of childhood-onset asthma.

Keyphrases

chronic obstructive pulmonary disease
lung function
allergic rhinitis
early life
genome wide
single cell
copy number
childhood cancer
cystic fibrosis
electronic health record
dna methylation
machine learning
transcription factor
genome wide identification