A change in the study evaluation paradigm reveals that larynx preservation compromises survival in T4 laryngeal cancer patients.
Gerhard DyckhoffPeter K PlinkertHeribert RamrothPublished in: BMC cancer (2017)
T4 laryngeal cancer patients who reject TL as a treatment option should be informed that their chance of organ preservation with primary conservative treatment is likely to result in a significantly worse outcome in terms of OS. Significant loss of survival in T4 patients after LP is also confirmed in recent literature.