Enhancement of Antioxidant Mechanisms and Reduction of Oxidative Stress in Chickens after the Administration of Drinking Water Enriched with Polyphenolic Powder from Olive Mill Waste Waters.
Aliki PapadopoulouKonstantinos PetrotosDimitrios StagosKonstantinos GerasopoulosAntonios MaimarisHaralampos MakrisIoannis KafantarisSotiria MakriEfthalia KerasiotiMaria HalabalakiVincent BrieudesGeorgia NtasiStylianos KokkasPavlos TzimasPanagiotis GoulasAlexander Mikhailovich ZakharenkoKirill Sergeyevich GolokhvastAristidis TsatsakisDemetrios KouretasPublished in: Oxidative medicine and cellular longevity (2017)
The aim of the study was to examine the effects of a polyphenolic powder from olive mill wastewater (OMWW) administered through drinking water, on chickens' redox status. Thus, 75 chickens were divided into three groups. Group A was given just drinking water, while groups B and C were given drinking water containing 20 and 50 μg/ml of polyphenols, respectively, for 45 days. The antioxidant effects of the polyphenolic powder were assessed by measuring oxidative stress biomarkers in blood after 25 and 45 days of treatment. These markers were total antioxidant capacity (TAC), protein carbonyls (CARB), thiobarbituric acid reactive species (TBARS) and superoxide dismutase activity (SOD) in plasma, and glutathione (GSH) and catalase activity in erythrocytes. The results showed that CARB and TBARS were decreased significantly in groups B and C, and SOD decreased in group B compared to that in group A. TAC was increased significantly in group C and GSH was increased in group B, while catalase activity was increased in groups B and C compared to that in group A. In conclusion, this is the first study showing that supplementation of chickens with polyphenols from OMWW through drinking water enhanced their antioxidant mechanisms and reduced oxidative stress-induced damage.
Keyphrases
- drinking water
- oxidative stress
- health risk
- health risk assessment
- heat stress
- dna damage
- diabetic rats
- anti inflammatory
- nitric oxide
- wastewater treatment
- small molecule
- hydrogen peroxide
- signaling pathway
- risk assessment
- heavy metals
- amino acid
- fluorescent probe
- protein protein
- endoplasmic reticulum stress
- heat shock
- heat shock protein