Limitations of current practices in detection of bacterially contaminated blood products associated with suspected septic transfusion reactions.
Isabella W MartinClaudia S CohnMeghan DelaneyMagali J FontaineAndrew W ShihNancy M Dunbarnull nullPublished in: Transfusion (2021)
The process of performing residual component culture is vulnerable to secondary contamination. The significance of microorganisms recovered from component culture cannot be interpreted in isolation. In the context of low prevalence of primary contamination of blood components, the positive predictive value of a positive component culture result is very low.