Genetic risk and incident venous thromboembolism in middle-aged and older adults following COVID-19 vaccination.

Junqing Xie Albert Prats-Uribe Maria Gordillo-Marañón Victoria Y Strauss Dipender Gill Daniel Prieto Alhambra

Published in: Journal of thrombosis and haemostasis : JTH (2022)

The strength of genetic susceptibility with post-COVID-19-vaccination VTE is similar to that seen in historical data. Additionally, the observed PRS-VTE associations were equivalent for adenovirus- and mRNA-based vaccines. These findings suggest that, at the population level, the VTE that occurred after the COVID-19 vaccination has a similar genetic etiology to the conventional VTE.

Keyphrases

venous thromboembolism
coronavirus disease
sars cov
direct oral anticoagulants
genome wide
copy number
respiratory syndrome coronavirus
cardiovascular disease
dna methylation
gene expression
atrial fibrillation
deep learning