Impact of different dose reduction criteria for anti-Xa direct oral anticoagulants on bleeding complications: A single center observational study.
Hidehira FukayaJun OikawaHironori NakamuraTazuru IgarashiTamami FujiishiNaruya IshizueTomoharu YoshizawaAkira SatohJun KishiharaShinichi NiwanoJunya AkoPublished in: Journal of arrhythmia (2022)
The patients with a standard dose of Apix had a higher incidence of minor bleeding events than the other dosages. A reduced dose of apixaban was not prone to being chosen because of the dose reduction criteria, which may have been associated with a higher minor bleeding rate in patients with Apix.