Association between Trypanosoma cruzi DTU TcII and chronic Chagas disease clinical presentation and outcome in an urban cohort in Brazil.
Marco Antonio Prates NielebockOtacílio C MoreiraSamanta Cristina das Chagas XavierLuciana de Freitas Campos MirandaAna Carolina Bastos de LimaThayanne Oliveira de Jesus Sales PereiraAlejandro Marcel Hasslocher-MorenoConstança BrittoLuiz Henrique Conde SangenisRoberto Magalhaes SaraivaPublished in: PloS one (2020)
TcII was the main T. cruzi DTU identified in chronic Chagas disease Brazilian patients (92.9%) with either cardiac, indeterminate or cardiodigestive forms, born at Southeast and Northeast regions. Other DTU found in much less frequency was TcVI (4.8%). TcII was also associated to patients that evolved with heart failure or sudden cardiac arrest, the two most common and ominous consequences of the cardiac form of Chagas disease.