Glycolytic reprogramming is involved in tissue remodeling on chronic rhinosinusitis.
Min-Sik JoHyun-Woo YangJoo-Hoo ParkJae-Min ShinIl-Ho ParkPublished in: PloS one (2023)
This study suggests that inhibition of the glycolytic enzyme and HIF-1α in nasal fibroblasts regulates myofibroblast differentiation and ECM generation associated with nasal mucosa remodeling.