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Interaction between Genetic Risk Scores for reduced pulmonary function and smoking, asthma and endotoxin.

Sinjini SikdarAnnah B WyssMi Kyeong LeeThanh T HoangMarie RichardsLaura E Beane FreemanChristine ParksPeter S ThorneJohn L HankinsonDavid M UmbachAlison Motsinger-ReifStephanie J London
Published in: Thorax (2021)
Evaluation of interactions using GRSs supports a greater impact of increased genetic susceptibility on reduced pulmonary function in the presence of smoking or asthma.
Keyphrases
  • chronic obstructive pulmonary disease
  • lung function
  • smoking cessation
  • genome wide
  • allergic rhinitis
  • copy number
  • gene expression
  • dna methylation