Short-term physical exercise controls age-related hyperinsulinemia and improves hepatic metabolism in aged rodents.

Vitor Rosetto MuñozR C GasparM C S ManciniR D de LimaR F L VieiraB M CrisolG C AntunesJ C S TrombetaI L P BonfanteF M SimabucoA S R da SilvaC R CavaglieriE R RopelleD E CintraJ R Pauli

Published in: Journal of endocrinological investigation (2022)

In conclusion, our data demonstrated that short-term aerobic exercise was able to control mechanisms related to hepatic fat accumulation and insulin sensitivity in aged rodents. These effects could contribute to late-life metabolic health and prevent the development/progression of age-related T2D.

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