Two-Year Incidence and Cumulative Risk and Predictors of Anal High-Grade Squamous Intraepithelial Lesions (anal precancer) among Women with HIV.
Elizabeth A StierMayuri JainHimanshu N JoshiTeresa M DarraghAshish A DeshmukhJeannette LeeMark H EinsteinNaomi JayJ Michael Berry-LawhornJoel M PalefskyTimothy WilkinGrant EllsworthAudrey L FrenchLuis F BarrosoRebecca LevineHumberto M GuiotM Katayoon RezaeiElizabeth ChiaoPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2023)
Detection of anal hrHPV or abnormal anal cytology are comparable predictors for 2-y-CR of anal hHSIL. The absence of anal hrHPV combined with negative cytology was predictive of a lower (but measurable) risk of developing anal hHSIL. These findings provide important data to inform anal cancer screening guidelines for WHIV.