Plasma circular RNA profiling of patients with gastric cancer and their droplet digital RT-PCR detection.

Tianwen LiYongfu ShaoLiyun FuYi XieLinwen ZhuWeiliang SunRui YuBingxiu XiaoJunming Guo

Published in: Journal of molecular medicine (Berlin, Germany) (2017)

A total of 343 circRNAs are differentially expressed between gastric cancer patients' plasma and healthy controls. Hsa_circ_0001017 and hsa_circ_0061276 are downregulated in gastric cancer tissues. The RT-ddPCR is a potent method for simultaneous detection of multiple circRNAs in plasma. Hsa_circ_0001017 and hsa_circ_0061276 are potential biomarkers for gastric cancer.

Keyphrases

real time pcr
single cell
loop mediated isothermal amplification
gene expression
label free
high throughput
anti inflammatory