Performance of non-invasive fibrosis scores in non-alcoholic fatty liver disease with and without morbid obesity.
Andreas DrolzStefan WolterMalte H WehmeyerFelix PiechaThomas HorvatitsJulian Schulze Zur WieschAnsgar W LohseOliver MannJohannes KluwePublished in: International journal of obesity (2005) (2021)
Our data suggest that FIB-4 score is an accurate predictor of advanced fibrosis in NAFLD throughout all BMI stages. Without adjustment, NFS tends to overestimate fibrosis in morbidly obese NAFLD patients. This problem may be solved by implementation of an upper BMI limit (for NFS) or adjustment of diagnostic thresholds.
Keyphrases
- liver fibrosis
- bariatric surgery
- weight loss
- obese patients
- metabolic syndrome
- end stage renal disease
- weight gain
- body mass index
- type diabetes
- ejection fraction
- chronic kidney disease
- insulin resistance
- primary care
- healthcare
- adipose tissue
- newly diagnosed
- prognostic factors
- electronic health record
- skeletal muscle
- data analysis
- deep learning