Quantitative brain stem assessment in discriminating neurodegenerative disorders from normal pressure hydrocephalus.

Charalampos GeorgiopoulosStergios PapadimitriouDag NyholmLena KilanderMalin LöwenmarkDavid FällmarJohan Virhammar

Published in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2024)

Our study questions MRPI's diagnostic performance in distinguishing PSP from iNPH. Simpler indices such as midbrain to pons ratio and midbrain area showed similar or better accuracy. However, all these indices displayed low sensitivity despite significant differences among PSP, MSA-P, and VaD.

Keyphrases

white matter
subarachnoid hemorrhage
resting state
multiple sclerosis
brain injury
clinical evaluation