MUM-1 immunohistochemistry has high accuracy and reliability in the diagnosis of chronic endometritis: a multi-centre comparative study with CD-138 immunostaining.

Ettore CicinelliSergio HaimovichDominique De ZieglerNili RazDana Ben-TzurAlessandra AndrisaniGuido AmbrosiniNico PicardiViviana CataldoMarco BalzaniRossana CicinelliMarco NoventaLoris MarinPantaleo GrecoLeonardo RestaCarlo SaccardiGiovanni BuzzaccariniAmerigo Vitaglianonull null

Published in: Journal of assisted reproduction and genetics (2021)

IHC for MUM-1 and CD-138 showed a similar accuracy for detecting endometrial stromal plasma cells. Notably, MUM-1 showed higher reliability in the paired comparison of the individual samples than CD-138. Thus, MUM-1 may represent a novel, promising add-on technique for the diagnosis of CE.

Keyphrases

induced apoptosis
nk cells
bone marrow
cell cycle arrest
cell death
cell proliferation
drug induced
clinical evaluation