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Cigarette Smoking and E-cigarette Use Induce Shared DNA Methylation Changes Linked to Carcinogenesis.

Chiara M S HerzogAllison JonesIona EvansJanhavi R RautMichal ZikanDavid CibulaAndrew WongHermann BrennerRebecca C RichmondMartin Widschwendter
Published in: Cancer research (2024)
The use of both cigarettes and e-cigarettes elicits cell- and exposure-specific epigenetic effects that are predictive of carcinogenesis, suggesting caution when broadly recommending e-cigarettes as aids for smoking cessation.
Keyphrases
  • smoking cessation
  • dna methylation
  • replacement therapy
  • gene expression
  • genome wide
  • single cell
  • cell therapy
  • stem cells
  • bone marrow
  • copy number