Novel Neurotechnological Interventions for Pediatric Drug-Resistant Epilepsy: Physician Perspectives.
Patrick J McDonaldViorica HrincuMary B ConnollyMark J HarrisonGeorge M IbrahimRobert P NaftelWinston ChiongFarhad UdwadiaJudy IllesPublished in: Journal of child neurology (2020)
This qualitative study investigated factors that guide physicians' choices for minimally invasive and neuromodulatory interventions as alternatives to conventional surgery or medical management for pediatric drug-resistant epilepsy. North American physicians were recruited to one of 4 focus groups at national conferences. Discussions were analyzed using qualitative content analysis. A pragmatic neuroethics framework was applied to interpret results. Discussions revealed 2 major thematic branches: (1) clinical decision making and (2) ethical considerations. Under clinical decision making, physicians emphasized scientific evidence and patient candidacy when assessing neurotechnologies for patients. Ongoing seizures without intervention was important for safety and neurodevelopment. Under ethical considerations, resource allocation, among other financial considerations for technology adoption, were considerable sources of pressure on decision making. Access to neurotechnology was a salient theme differentiating Canadian and American contexts. When assessing novel neurotechnological interventions for pediatric drug-resistant epilepsy, physicians balance clinical and ethical factors to guide decision making and best practice.
Keyphrases
- drug resistant
- decision making
- primary care
- multidrug resistant
- acinetobacter baumannii
- minimally invasive
- physical activity
- healthcare
- systematic review
- prognostic factors
- ejection fraction
- newly diagnosed
- magnetic resonance imaging
- magnetic resonance
- drinking water
- clinical trial
- quality improvement
- case report
- study protocol
- atrial fibrillation
- high resolution
- computed tomography
- single cell
- mass spectrometry
- patient reported outcomes
- coronary artery disease
- single molecule
- atomic force microscopy
- advance care planning