The relationship between liver histology and thyroid function tests in patients with non-alcoholic fatty liver disease (NAFLD).

Roberta D'AmbrosioIrene CampiMarco MaggioniRiccardo PerbelliniEnza GiammonaRoberta StucchiMarta BorghiElisabetta DegasperiAnnalisa De SilvestriLuca PersaniLaura FugazzolaPietro Lampertico

Published in: PloS one (2021)

Hypothyroidism was highly prevalent in NAFLD patients, and was associated with increased NAFLD activity, but not with fibrosis and steatosis severity. Thus, thyroid dysfunction might play a direct and/or indirect in the pathogenesis of NAFLD and NASH.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
insulin resistance
high fat diet
liver fibrosis
patient reported outcomes