Impact of Oral Metronidazole, Vancomycin, and Fidaxomicin on Host Shedding and Environmental Contamination with Clostridioides difficile.
Nicholas A TurnerBobby G WarrenMaria F Gergen-TeagueRachel M AddisonBechtler AddisonWilliam A RutalaDavid J WeberDaniel J SextonDeverick J AndersonPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
Fidaxomicin, and to a lesser extent vancomycin, reduces C. difficile shedding and contamination of the hospital environment relative to metronidazole. Treatment choice may play a role in reducing healthcare-associated C. difficile transmission.