Effects of isoflurane anesthesia on addictive behaviors in rats.
Seong Shoon YoonBong Hyo LeeSeong Ho LeeSeong Hun ChoiSeon-Ju JeongSang Chan KimChae Ha YangPublished in: Psychopharmacology (2022)
The results provided evidence that isoflurane decreases cocaine- and nicotine-reinforced responses, while isoflurane effect is not selective for cocaine- and nicotine-maintained responding. These results suggest that isoflurane inhibitions of cocaine- and nicotine-maintenance responses may be related to decreased effects of dopamine, and further investigation will need to elucidate this relationship.