Combination therapy berberine-fluconazole microparticles-based to treat candidiasis infections.

Ludmila Pini Simões GobbiEliana Harue Endo CostaCarla Maria Mariano FernandezFabiana Bruschi LorenzettiDyenefer Pereira FonsecaAnderson Valdiney GomesDebora Cristina BaldoquiCleverton de Souza FernandesTânia Ueda-NakamuraCelso Vataru NakamuraMarli Miriam de Souza LimaBenedito Prado Dias Filho

Published in: Journal of applied microbiology (2023)

Alginate microparticles containing BBR and FLU were obtained and incorporated in a vaginal cream and artificial saliva. Both formulations showed good stability, antifungal effects and organoleptic characteristics which suggest that BBR-FLU microparticles in formulations have potential as antifungal therapy.

Keyphrases

candida albicans
combination therapy
stem cells
risk assessment
bone marrow
cell therapy