Transdermal Delivery of Telmisartan: Formulation, in vitro, ex vivo, Iontophoretic Permeation Enhancement and Comparative Pharmacokinetic Study in Rats.
Mahmoud Hassan TeaimaRehab AbdelmonemYomna A AdelMohamed A El-NabarawiTayseer M El-NawawyPublished in: Drug design, development and therapy (2021)
The transethosomal formulation of telmisartan enhanced its transdermal absorption and increased its bioavailability as well. Iontophoresis was used to increase maximum plasma concentration and reduce Tmax by half.
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