Caspase Cascade Activation During Apoptotic Cell Death of Human Lung Carcinoma Cells A549 Induced by Marine Sponge Callyspongia aerizusa.

Yuni Elsa HadisaputriRheza AndikaIyan SopyanAde ZuhrotunRani MaharaniRachmaniar RachmatRizky Abdulah

Published in: Drug design, development and therapy (2021)

These findings suggest that the compounds in CA extract possess the ability to induce apoptotic cell death in A549 cells and could become a promising candidate for future anticancer therapy.

Keyphrases

cell death
cell cycle arrest
induced apoptosis
oxidative stress
current status
endoplasmic reticulum stress
signaling pathway
protein kinase