High Diagnostic Accuracy of Epigenetic Imprinting Biomarkers in Thyroid Nodules.
Huixiong XuYifeng ZhangHongxun WuNing ZhouXing LiJohn P PinedaYun ZhuHuijun FuMing YingShufang YangJiandong BaoLulu YangBingjie ZhangLehang GuoLiping SunFeng LuHanxiang WangYing HuangTiantong ZhuXiaonan WangQing WeiChunjun ShengShen QuZhongwei LvDong XuQian LiYongling DongJianwu QinTong ChengMingzhao XingPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)
This imprinting biomarker-based test can effectively distinguish malignant from benign thyroid nodules. The high PPV and NPV make the test both an excellent rule-in and rule-out diagnostic tool. With such a diagnostic performance and its technical simplicity, this novel thyroid molecular test is clinically widely applicable.
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