Lack of drug interaction between levetiracetam and high-dose methotrexate in patients with lymphoma.
Catherine E MartinJason N BarretoAmanda G PawlentyMichael W RuffIvan D CarabenciovKristin C MaraCarrie A ThompsonPublished in: Pharmacotherapy (2021)
High-dose methotrexate administered with concomitant levetiracetam was not associated with increased risk for delayed MTX elimination or AKI. These results support that levetiracetam and HDMTX are safe for coadministration.