Carriage of Shiga toxin phage profoundly affects Escherichia coli gene expression and carbon source utilization.

Petya BergerIvan U KouzelMichael BergerNadja HaarmannUlrich DobrindtGerald B KoudelkaAlexander Mellmann

Published in: BMC genomics (2019)

Our study reveals a profound impact of the Stx phage carriage on E. coli carbon source utilization. The Stx2a prophage appears to reprogram the carbon metabolism of its bacterial host by turning down aerobic metabolism in favour of mixed acid fermentation.

Keyphrases

escherichia coli
gene expression
pseudomonas aeruginosa
biofilm formation
klebsiella pneumoniae
cystic fibrosis
staphylococcus aureus
multidrug resistant
candida albicans