Impact of maternal obesity on placental transcriptome and morphology associated with fetal growth restriction in mice.

Daniela de Barros MucciLaura C KusinskiPhoebe WilsmoreElena LocheLucas C PantaleãoThomas J AshmoreHeather L BlackmoreDenise S Fernandez-TwinnMaria das Graças T do CarmoSusan E Ozanne

Published in: International journal of obesity (2005) (2020)

Maternal obesity results in abnormal placental LZ development and impaired vascularization, which may mediate the observed FGR through reduced transfer of nutrients across the placenta.

Keyphrases

high fat diet induced
insulin resistance
birth weight
weight gain
metabolic syndrome
weight loss
type diabetes
pregnancy outcomes
gene expression
heavy metals
rna seq
genome wide
body mass index
skeletal muscle
adipose tissue
tissue engineering
physical activity