MFN2 overexpression in skeletal muscles of young and old mice causes a mild hypertrophy without altering mitochondrial respiration and H 2 O 2 emission.
Marina CefisManon DargegenVincent MarcangeliShima TaherkhaniMaude DulacJean-Philippe Leduc-GaudetDominique MayakiSabah N A HussainGilles GouspillouPublished in: Acta physiologica (Oxford, England) (2024)
MFN2 overexpression may be a viable approach to mitigate aging-related muscle atrophy and may have applications for other muscle disorders.