Disease-stabilizing treatment based on all-trans retinoic acid and valproic acid in acute myeloid leukemia - identification of responders by gene expression profiling of pretreatment leukemic cells.

Håkon ReikvamRandi HovlandRakel Brendsdal ForthunSigrid ErdalBjørn Tore GjertsenHanne FredlyØystein Bruserud

Published in: BMC cancer (2017)

ClinicalTrials.gov no. NCT00175812 ; EudraCT no. 2004-001663-22, registered September 9, 2005 and ClinicalTrials.gov no. NCT00995332 ; EudraCT no. 2007-2007-001995-36, registered October 14, 2009.

Keyphrases

induced apoptosis
genome wide
genome wide identification
cell cycle arrest
acute myeloid leukemia
copy number
endoplasmic reticulum stress
cell death
dna methylation
signaling pathway
transcription factor
combination therapy
replacement therapy