Impact of the change in the antitubercular regimen from three to four drugs on cure and frequency of adverse reactions in tuberculosis patients from Brazil: A retrospective cohort study.
María Belen ArriagaNinfa Marlen Chaves-TorresNelia C N AraujoSimone C C CaldasBruno Bezerril AndradeEduardo M NettoPublished in: PloS one (2019)
The patients treated with the four-drug regimen exhibited increased risk of ADRs compared to those who received the three-drug regimen, and especially in patients older than 30 years of age.