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Impact of the change in the antitubercular regimen from three to four drugs on cure and frequency of adverse reactions in tuberculosis patients from Brazil: A retrospective cohort study.

María Belen ArriagaNinfa Marlen Chaves-TorresNelia C N AraujoSimone C C CaldasBruno Bezerril AndradeEduardo M Netto
Published in: PloS one (2019)
The patients treated with the four-drug regimen exhibited increased risk of ADRs compared to those who received the three-drug regimen, and especially in patients older than 30 years of age.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • prognostic factors
  • mycobacterium tuberculosis
  • physical activity
  • human immunodeficiency virus
  • hiv infected
  • patient reported