Isolation of senescent cells by iodixanol (OptiPrep) density gradient-based separation.

Published in: Cell proliferation (2019)

Analysing pure cultures of chemotherapy-induced senescent versus non-responsive cancer cells will increase our knowledge on chemotherapeutic mechanisms of action, and help refine current therapeutic strategies.

Keyphrases

chemotherapy induced
induced apoptosis
cell cycle arrest
healthcare
endoplasmic reticulum stress
signaling pathway
oxidative stress
cell proliferation
pi k akt