Assessing the involvement of the placental microbiome and virome in preeclampsia using non coding RNA sequencing.
Liron YoffeAmir A KupermanOfer IsakovDanielle HaguelAvital L PolskyLuba FarberovNir PillarVyacheslav GurevichIzhak HavivNoam ShomronPublished in: Journal of perinatal medicine (2021)
Our results suggest that the bacterial and viral abundance in the placenta may have only limited involvement in the pathogenesis of preeclampsia. The evidence of a heterogenic bacterial RNA composition in the various placental locations warrants further investigation to capture the true nature of the placental microbiome.