The benefit of adjuvant chemotherapy following pancreaticoduodenectomy for pancreatic adenocarcinoma depends on response to neoadjuvant therapy.
Elizabeth L CarpenterSpencer G Van DecarPatrick M McCarthyFranklin A ValderaAlexandra M AdamsAnne E O'SheaTodd R SmolinskyKatryna ThomasGuy T CliftonTimothy E NewhookGeorge E PeoplesDaniel W NelsonTimothy J VreelandPublished in: Journal of surgical oncology (2024)
Response to NAT appears to correlate with the benefit of AT following pancreaticoduodenectomy; patients who have a favorable response to NAT may not benefit from AT.