Cerebrospinal Fluid Biomarkers in Patients With Alcohol Use Disorder and Persistent Cognitive Impairment.

Julien AzuarElodie Bouaziz-AmarEmmanuel CognatJulien DumurgierVirgile Clergue-DuvalThomas BarréJihed AmamiEric HispardFrank BellivierClaire PaquetFlorence VorspanFrank Questel

Published in: Alcoholism, clinical and experimental research (2021)

This study revealed a high prevalence of AD in alcohol-dependent patients with persistent cognitive deficits and several anomalies in their CSF profiles. Thus, it is important to consider AD in the differential diagnosis of persistent cognitive deficits in patients with alcohol dependence and to use CSF biomarkers in addition to imaging and neuropsychological testing to evaluate alcohol-related cognitive impairment.

Keyphrases

cognitive impairment
cerebrospinal fluid
alcohol use disorder
alcohol consumption
high resolution
mild cognitive impairment
single cell
fluorescence imaging