A Photoinduced Radical Cascade Cyclization for the Synthesis of Angularly Fused Tricyclic Compounds.

A photoinduced electron transfer (PET)-triggered cascade reaction has been devised for the conversion of second-generation enol silyl ethers into angularly fused tricyclic scaffolds. Utilizing readily available and cost-effective DCA and phenanthrene as the catalytic systems, this cascade transformation is achieved with high efficiency. The reaction demonstrates a good substrate scope and excellent stereoselectivity, thereby enriching the realm of PET-induced cascade reactions. Additionally, the radical adducts generated through this process can serve as valuable subunits for the synthesis of complex molecules.