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Novel kinase platform for the validation of the anti-tubercular activities of Pelargonium sidoides (Geraniaceae).

V LukmanS W OdeyemiR L RothL MbabalaN TshililoN M VlokM J B DewarColin Kenyon
Published in: BMC biotechnology (2020)
This study suggests P. sidoides is potentially a source of anti-tubercular compounds and the Mtb kinase platform has significant potential as a tool for the subsequent screening of P. sidoides extracts and plant extracts in general, for compound identification and elaboration by selected extract target inhibitor profiling.
Keyphrases
  • high throughput
  • protein kinase
  • mycobacterium tuberculosis
  • tyrosine kinase
  • pulmonary tuberculosis
  • risk assessment
  • cell wall