SHED-derived exosomes improve the repair capacity and osteogenesis potential of hPDLCs.

Menghong WangJie LiYanyan YeDuanjing Chen Jinglin Song

Published in: Oral diseases (2022)

Exosomes from SHED can improve cell proliferation, migration, cell cycle, apoptosis, and osteogenic differentiation of hPDLCs, which highlights the therapeutic value of this bioactive component in the regeneration of periodontal tissues using hPDLCs in clinical practice.

Keyphrases

cell cycle
cell proliferation
stem cells
mesenchymal stem cells
clinical practice
oxidative stress
gene expression
endoplasmic reticulum stress
cell cycle arrest
cell death
pi k akt
bone marrow
signaling pathway
risk assessment
climate change