Intratumoral Delivery of STING Agonist Results in Clinical Responses in Canine Glioblastoma.

C Elizabeth Boudreau Hinda NajemMartina OttCraig HorbinskiDexing FangChase M DeRayJonathan M LevineMichael A CurranAmy B Heimberger

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)

Intratumoral STING agonist (IACS-8779) administration was well tolerated in dogs with glioblastoma to a dose of 15 μg. Higher doses of IACS-8779 were associated with radiographic responses.

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