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PI3K/AKT/SERBP-1 pathway regulates Alisma orientalis beverage treatment of atherosclerosis in APOE -/- high-fat diet mice.

Ruiyi LiuYan SunDong DiXiyuan ZhangBoran ZhuHaoxin Wu
Published in: Pharmaceutical biology (2023)
AOB had therapeutic effects for AS by improving blood lipids and inhibition of the PI3K/AKT/SERBP-1 pathway in the liver. This study provides new ideas for the treatment of AS, as well as new evidence for the clinical application of AOB.
Keyphrases
  • high fat diet
  • pi k akt
  • signaling pathway
  • insulin resistance
  • adipose tissue
  • cell proliferation
  • type diabetes
  • metabolic syndrome
  • combination therapy
  • cognitive decline
  • skeletal muscle