HPV-independent and HPV-associated vulvar squamous cell carcinoma: two different cancers.

Lois EvaLynn SadlerJohn Md ThompsonSukwinder SahotaKah Leng FongRonald W JonesSusan M Bigby

Published in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2022)

HPV-independent vulvar squamous cell carcinomas present more frequently in older women than HPV-associated tumors. However, the poorer prognosis is independent of age and stage, with worse outcomes even in early stage disease.

Keyphrases

high grade
early stage
squamous cell carcinoma
squamous cell
cervical cancer screening
sentinel lymph node
type diabetes
young adults
lymph node
insulin resistance
skeletal muscle