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Influence of sperm cryopreservation on sperm motility and proAKAP4 concentration in mice.

Auke BoersmaJasmin PrimusBettina WagnerVeronika BroukalLill AndersenBarbara PachnerMaik DahlhoffThomas RülickeKerstin E Thonhauser
Published in: Reproductive medicine and biology (2022)
ProAKAP4 levels in epididymal mouse spermatozoa were unaffected by cryopreservation, highlighting the robustness of this parameter as a potentially time-independent marker for sperm motility and fertility. The high individual variation in proAKAP4 levels supports the potential role of proAKAP4 as a marker for sperm quality, though we found no positive, and even negative relationships between proAKAP4 levels and some sperm motility parameters. Future studies have to investigate the significance of proAKAP4 as an indicator for fertility in mice.
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