T follicular helper cells improve the response of patients with chronic hepatitis B to interferon by promoting HBsAb production.

Yong LiuXintong HuXiaoli HuLei YuHuifan JiWanyu LiYanjun CaiGenhong ChengYanfang Jiang

Published in: Journal of gastroenterology (2022)

TFH cells, particularly those with CD40L expression, stimulate B-cell differentiation and improve the HBsAg seroconversion rate in patients with CHB treated with PEG-IFN-α monotherapy.

Keyphrases

induced apoptosis
cell cycle arrest
hepatitis b virus
dendritic cells
immune response
cell death
drug delivery
oxidative stress
open label
newly diagnosed