Defective CD19+CD24hiCD38hi transitional B-cell function in patients with relapsing-remitting MS.

Maria T CencioniRehiana AliRichard St John NicholasPaolo A Muraro

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2020)

CD19+CD24hiCD38hi transitional B cells physiologically represent the most potent regulatory B-cell subset and are functionally defective in patients with RRMS, an abnormality that may contribute to the immune pathological process.

Keyphrases

multiple sclerosis
disease activity
transcription factor
mass spectrometry
anti inflammatory
rheumatoid arthritis