DLGAP1-AS2-Mediated Phosphatidic Acid Synthesis Activates YAP Signaling and Confers Chemoresistance in Squamous Cell Carcinoma.

Yabing Nan Qingyu Luo Xiaowei WuShi LiuPengfei ZhaoWan ChangAiping Zhou Zhihua Liu

Published in: Cancer research (2022)

This study identifies D-AS2 as a targetable lipid-related long noncoding RNA that increases phospholipase D activity to promote YAP signaling, triggering chemoresistance in SCC.

Keyphrases

long noncoding rna
squamous cell carcinoma
genome wide
radiation therapy
lymph node metastasis
dna methylation
cancer stem cells
rectal cancer
drug induced