Centrifuged supernatants from FNA provide a liquid biopsy option for clinical next-generation sequencing of thyroid nodules.
Wenrui YeBrette HanniganStephanie ZallesMeenakshi MehrotraBedia A BarkohMichelle D WilliamsMaria E CabanillasBeth Edeiken-MonroePeter HuDzifa DuoseIgnacio I WistubaL Jeffrey MedeirosJohn StewartRajyalakshmi LuthraSinchita Roy-ChowdhuriPublished in: Cancer cytopathology (2019)
This study provides evidence that FNA supernatants can be used as a surrogate for thyroid molecular testing to improve diagnostic accuracy in indeterminate nodules, provide prognostic/predictive information, and improve overall patient management.