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Centrifuged supernatants from FNA provide a liquid biopsy option for clinical next-generation sequencing of thyroid nodules.

Wenrui YeBrette HanniganStephanie ZallesMeenakshi MehrotraBedia A BarkohMichelle D WilliamsMaria E CabanillasBeth Edeiken-MonroePeter HuDzifa DuoseIgnacio I WistubaL Jeffrey MedeirosJohn StewartRajyalakshmi LuthraSinchita Roy-Chowdhuri
Published in: Cancer cytopathology (2019)
This study provides evidence that FNA supernatants can be used as a surrogate for thyroid molecular testing to improve diagnostic accuracy in indeterminate nodules, provide prognostic/predictive information, and improve overall patient management.
Keyphrases
  • fine needle aspiration
  • ultrasound guided
  • case report
  • copy number
  • ionic liquid
  • healthcare
  • gene expression
  • single molecule