Neonatal hypoxia-ischemia in rat elicits a region-specific neurotrophic response in SVZ microglia.
Urs FischCatherine BrégèreFlorian GeierLaurie ChichaRaphael GuzmanPublished in: Journal of neuroinflammation (2020)
Microglia are an inherent cellular component of the early postnatal SVZ and undergo developmental changes that are affected on many aspects by neonatal HI injury. Our results demonstrate that early postnatal SVZ microglia are sensitive to HI injury and display a long-lasting region-specific response including neurotrophic features.