High-Intensity Focused Ultrasound (HIFU) Triggers Immune Sensitization of Refractory Murine Neuroblastoma to Checkpoint Inhibitor Therapy.
Avinash ErankiPriya SrinivasanMario RiesAeRang KimChristopher A LazarskiChristopher T RossiTatiana D KhokhlovaEmmanuel WilsonSusan M KnoblachKarun V SharmaBradford J WoodChrit MoonenAnthony D SandlerPeter C W KimPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)
Mechanical fractionation of tumors using HIFU can effectively induce immune sensitization in a previously unresponsive murine neuroblastoma model and promises a novel yet efficacious immunoadjuvant modality to overcome therapeutic resistance.