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Population pharmacokinetics of ganciclovir and valganciclovir in paediatric solid organ and stem cell transplant recipients.

Bénédicte FranckJean Baptiste WoillardYves ThéorêtHenrique BittencourtEmile DemersAnnabelle BriandPierre MarquetAnne-Laure LapeyraquePhilippe OvetchkineJulie Autmizguine
Published in: British journal of clinical pharmacology (2021)
This is the first POPPK model developed in children with either SOT or SCT. Concentration target achievement was low, suggesting a potential benefit for therapeutic drug monitoring to ensure optimal exposure.
Keyphrases
  • stem cells
  • young adults
  • intensive care unit
  • emergency department
  • human health
  • risk assessment
  • mesenchymal stem cells
  • cell therapy
  • bone marrow