Population pharmacokinetics of ganciclovir and valganciclovir in paediatric solid organ and stem cell transplant recipients.
Bénédicte FranckJean Baptiste WoillardYves ThéorêtHenrique BittencourtEmile DemersAnnabelle BriandPierre MarquetAnne-Laure LapeyraquePhilippe OvetchkineJulie AutmizguinePublished in: British journal of clinical pharmacology (2021)
This is the first POPPK model developed in children with either SOT or SCT. Concentration target achievement was low, suggesting a potential benefit for therapeutic drug monitoring to ensure optimal exposure.